THOMAS R. IOERGER

Associate Professor

Email: ioerger@cse.tamu.edu
Phone: 979-845-0161
Office: HRBB 322C
http://faculty.cse.tamu.edu/ioerger/

Ph.D., Computer Science, University of Illinois at Urbana-Champaign, 1996
M.S., Computer Science, University of Illinois at Urbana-Champaign 1992
B.S., Molecular and Cell Biology, Pennsylvania State University, 1989

RESEARCH INTERESTS

Artificial intelligence, machine learning, intelligent agents, bioinformatics

SELECTED RESEARCH SUPPORT

"Structures of Mtb Proteins Conferring Susceptibility to known MTB Inhibitors," NIH, (Sacchettini, PI), 7/1/10-6/30/15.

"Structural Genomics of Persistence Targets from Mycobacterium tuberculosis", NIH, (Sacchettini, PI), 04/01/06 - 03/31/11.

"Integrated Methods for Tuberculosis Drug Discovery", Bill & Melinda Gates Foundation, (Sherman, PI), 9/1/2007 - 8/31/2010.

"Chemical Validation of Malate Synthase as a Drug Target for Persistent TB", Global Alliance for TB Drug Development, (Sacchettini, PI), 8/17/2007 - 8/16/09.

"Automated X-ray Crystallography for Structural Genomics," NIH, 4/1/01 - 3/31/05.

AWARDS

TEES Faculty Fellow, 2004-2005

Graduate Teaching Excellence Award, Dept. of Computer Science, Texas A&M University, 2001

NSF Graduate Fellowship, 1990 - 1993

EXPERIENCE

Associate Professor, Department of Computer Science and Engineering, Texas A&M University, September 2002 - present

Assistant Professor, Department of Computer Science, Texas A&M University, September 1996 - 2002

PROFESSIONAL ACTIVITIES AND SERVICE

Finance Chair for Fuzz-IEEE 2000, San Antonio

Reviewer for: Machine Learning, IEEE Trans. on Knowledge and Data Engineering, IEEE Trans. on Multimedia, Acta Crystallographica

NIH Study Section (proposal reviewer)

Member of American Association for Artificial Intelligence, International Society for Computational Biology, and American Association for the Advancement of Science

SELECTED PUBLICATIONS

Ioerger, T.R., Feng, Y., Ganseula, K., Chen, X., Dobos, K.M., Fortune, S., Jacobs, W.R., Mizrahi, V., Parish, T., Rubin, E., Sassetti, C. and Sacchettini, J.C. (2010), "Variation Among Genome Sequences of H37Rv Strains of M. tuberculosis from Multiple Laboratories," Journal of Bacteriology, 192:3645-3653.

Ioerger, T.R., Koo, S., No, E.-G., Chen, X., Larsen, M.H., Jacobs, W.R., Pillay, M., Sturm, A.W., and Sacchettini, J.C., "Genome Analysis of Multi- and Extensively-Drug-Resistant Tuberculosis from KwaZulu-Natal," South Africa, PLoS ONE, 4(11):e7778, 2009.

Cho, Y., Ioerger, T.R. and Sacchettini, J.C., "Discovery of Novel Nitrobenzothiazole Inhibitors for M. tuberculosis ATP Phosphoribosyl Transferase (HisG) through Virtual Screening," Journal of Medicinal Chemistry, 51(19):5984-5992, 2008.

Sacchettini, J., and Ioerger, T., "TEXTAL: Automated Crystallographic Protein Structure Determination," Proc. 17th Conference on Innovative Applications in Artificial Intelligence (IAAI-05), 1483-1490, 2005.

Gopal, K., Romo, T., Sacchettini, J.C., and Ioerger, T.R., "Determining Relevant Features to Recognize Electron Density Patterns in X-ray Protein Crystallography," Journal of Bioinformatics and Computational Biology, 3(3):645-676, 2005.